Find out more about the epidermal cell regeneration and how microneedling supports it.
Microneedling removes dead and loose skincells. UV rays as well as free radicals can therefore penetrate the skin much easier and even cause post inflammatory hyperpigmentation by trigerring the melanocytes. Therefore the right skincare and UV protection after microneedling is very important.
The micro channels caused by the Dermarollers increase the active ingredient infiltration into the deeper skin layers to a maximum. All tested Dermarollers also caused an increased absorption of the tested active substances into the horny skin layer (stratum corneum).
During a Microneedling treatment the outer layers of skin (the epidermis and depending on needle length also the dermis) get minimally invasive punctured, therefore no open wounds occur. The puncturing channels close quickly again. The body's own repair process for the renewal of injured skin tissue allows the restoration of epithelial function within a short time. Because of the associated collagen production in the skin, this process is also called "percutaneous collagen induction" (PCI) or "collagen induction therapy" (CIT).
The systematic absorption of active substances through the skin is very limited and is largely prevented by the barrier of the stratum corneum. The Universities of Marburg and Jena have provided evidence that even small liposomes penetrate the skin with only 0.3% in a period of 12 hours. If, on the other hand, the stratum corneum is treated with the Dermaroller, the penetrating amount of an active ingredient increases by more than 1000%. In 2000 the University of Marburg/Germany has proven the efficacy of transdermal delivery with the Dermaroller. Source: University study, 2000, Marburg (Germany)